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3 recalls covering model years 2019, 2020, 2025. To check whether your vehicle is affected, look up your 17-character VIN at nhtsa.gov/recalls — a recall may apply only to some vehicles of a given year.
The system that controls the infotainment screen may reset on its own while the vehicle is being driven. When this happens, the instrument panel display can go blank, meaning the driver can no longer see it.
On certain Mercedes-Benz E 400 4MATIC, E 450 4MATIC, E 450 4MATIC Coupe, and S 560 4MATIC vehicles, a universal joint in the drive shaft may break. If this joint breaks, the vehicle can suddenly lose the power that turns the wheels while it is being driven, meaning the car stops being able to move under its own power at that moment.
A metal bracket that connects to the rear axle on some E 350 and E 350 4MATIC vehicles may not have been welded onto the axle correctly. Because of this faulty weld, the bracket could separate from the rear axle carrier while the vehicle is being driven. Mercedes-Benz dealers will replace the entire rear axle carrier on affected vehicles, at no cost to the owner.
⚠ NHTSA advises: do not drive this vehicle until repaired.
Recalls and NHTSA owner complaints for each model year, side by side. Complaints are unverified owner reports, and better-selling or older years naturally collect more — read this as a record, not a ranking.
| Model year | Recalls | High / critical | Do-not-drive / park-outside | Complaints | Crashes | Fires | Injuries |
|---|---|---|---|---|---|---|---|
| 2019 | 1 | 1 | 0 | 3 | 0 | 0 | 0 |
| 2020 | 1 | 1 | 0 | 3 | 0 | 0 | 0 |
| 2025 | 2 | 2 | 1 | 2 | 0 | 0 | 0 |
NHTSA lists 3 safety recalls covering the 2019–2025 Mercedes-Benz E 450 4MATIC. 3 of them are rated high or critical on this site. The most recent is "Mercedes-Benz Instrument Panel Display May Go Blank" (NHTSA campaign 26V281000), reported May 1, 2026.
The 2025 Mercedes-Benz E 450 4MATIC has the most, with 2 recalls. The 2019 model year has the fewest of the years we cover, with 1. Newer model years have had less time to collect recalls, so a low count on a recent year is not a guarantee.
Yes. 1 Mercedes-Benz E 450 4MATIC recall carries a do-not-drive or park-outside advisory from NHTSA: Mercedes-Benz E 350 Rear Axle Weld Defect (24V941000). These apply only to the affected vehicles, so check your VIN.
Enter your 17-character VIN at nhtsa.gov/recalls. A recall often applies to only some vehicles of a model year, and the VIN lookup shows the ones still unrepaired on your car. Recall repairs are free at any franchised Mercedes-Benz dealer, including for second owners.
Recalls and complaint record for one model year at a time: